Endocrine Abstracts

Introduction: The adrenocortical carcinoma (ACC) is a primary malignant tumor developed in depends of the adrenal cortex, defined by a Weiss score ≥3. Despite the therapeutic progress, its prognosis is still severe.Patients and methods: This retrospective descriptive study evaluated 4 patients with adrenal corticosteroid followed in the endocrinology department of Sfax - Tunisia between 2010 and 2018.Results: There were 3 wom...

Intoduction: Pitiutary tumor is considered as the first etiology responsable of secondary hypopituitarism. Hypogonadotropic hypogonadism is the most commonly reported lesion.Meterials and methods: It is a retrospective study including 77 cases of prolactinoma. The data collection was done over 17 years, between 2000 and 2017.Results: Gonadotropic deficiency was confirmed in 48 patients (63.6%). A significant negative correlation wa...

Introduction: Pheochromocytoma occurs in 0.1–5.7% of patients with Neurofibromatosis type 1(NF1). We report two cases of adrenal pheochromocytoma in patients with NF1.Observation: A 46 year-old male was admitted to our department for further examinations of an adrenal mass. The CT-scan showed two well-defined right adrenal masses measuring each 128×87×86 mm and 60×52×37 mm with central necrosis and calcifications in the biggest o...

Introduction:: The association of breast cancer and neuroendocrine tumours, in particular pheochromocytoma, is rarely described in the literature. We report a case in a particular context.Observation: This is a 53-year-old patient treated with 6 courses of chemotherapy for T2N3cM0 infiltrating breast carcinoma. She was admitted to our endocrinology department for exploration of a left adrenal incidentaloma, objectified in the extension assessment, measur...

Introduction: Prolactinoma is the most common secretory pituitary adenomas. It has clinical and biological characteristics that depend on age, gender and tumor size. Prolactinoma of the old subject is a rare clinical form that was not sufficiently treated in the literature.Materiels and methods: It is a retrospective study including 77 cases of prolactinoma among which 3 cases aged over than 65 years. The collection of data was made between 2000 and 2017...

Introduction: Infertility is a classic consequence of prolactinoma in women. The treatment of hyperprolactinemia allows the restoration of ovulatory cycles and therefore of fertility in 80–90% of cases.Methods and materials: The study is a retrospective cohort study done over 17 years from 2000 to 2017. It includes 77 cases of prolactinomas among which 12 women had one or more pregnancies after the diagnosis of prolactinoma.Re...

IntroductionMitochondrial diseases are a clinically heterogeneous group of disorders that arise as a result of dysfunction of the mitochondrial respiratory chain.it is genetically heterogeneous diseases characterized by multisystem involvement. Thus, its clinical description is incomplete. The aim of this case report is to highlight the association between mitochondrial diabetes and severe hypertriglyceridemia. In this study, we describe the case of a 22...

IntroductionAcute pancreatitis (AP) is the most common affection of the pancreas, it often leads to glycemic disorders. On the other hand, diabetic ketoacidosis (DKA) is associated with nonspecific increase in serum amylase levels. The aim of this study was to evaluate the clinical characteristics of acute AP concomitant with DKA.MethodsWe conducted a retrospective and descriptive analysis of clinical records...

IntroductionSevere hypertriglyceridemia (sHTG) (plasma triglycerides b 10 g/l) is a rare but pernicious and understudied condition.ObjectiveOur objective was to evaluate the etiology, characteristics, and complications of sHTG.MethodsIt’s a retrospective study including 10 patients with (sHTG) diagnosed between 1998 and 2020, at the department of endocri...